Relationship Between Family Support and Colorectal Cancer Patients' Motivation for Undergoing Chemotherapy
Abstract
Globally, colorectal cancer is one of the most highly prevalent cancers according to the World Health Organization, with the majority of patients undergoing chemotherapy. Various studies show that more than 70% of patients experience significant physiological impacts such as fatigue, nausea, and disruption of daily activities, while approximately 30% experience psychological disorders such as anxiety and depression. Furthermore, more than 60% of patients require family support during treatment. This demonstrates that the impact of chemotherapy is multidimensional, encompassing physical, psychological, and social aspects, necessitating a comprehensive care approach that includes family involvement. The purpose of this study was to determine the relationship between family support and motivation of colorectal cancer patients undergoing chemotherapy. The study design used an observational analytic design with a cross-sectional approach. The study population comprised all 55 colorectal cancer patients undergoing chemotherapy in the Rosella 2 Room at Dr. Soetomo Hospital, Surabaya. A sample of 48 people was taken using the Simple Random Sampling technique. Data analysis used the Spearman Rho correlation test. The results showed that of the 48 respondents, 43 had high family support and 42 had strong motivation. Bivariate analysis showed a significant relationship between family support and patient motivation to undergo chemotherapy. The results of the Spearman Rho test showed a rho value of 0.902 and a significance value of P = 0.000 (< 0.05). The active role of nurses in providing education to families and patients is very important in providing information related to chemotherapy. So that it can provide a sense of security, comfort, and trust in nurses. Thus, patients have strong motivation, high life expectancy, and increased family enthusiasm in accompanying the treatment process.
References
Mahajan, N. M., Chaudhari, A., More, S. & Gangane, P. Nanotherapeutics for colon cancer. Photophysics Nanophysics Ther. 251–268 (2022) doi:10.1016/B978-0-323-89839-3.00005-1.
Nuridah, N., Saleh, A. & Kaelan, C. Analisis Faktor-faktor yang Berhubungan dengan Kualitas Hidup Penderita Kanker Kolorektal di Rumah Sakit Kota Makassar. J. Keperawatan Indones. 22, 83–91 (2019).
Pakpahan, R. D. Kualitas Hidup Pasien Kanker Kolorektal yang Baru Menjalani Kolostomi dengan Endstoma. (2015).
Del Mastro, L. et al. Impact of two different dose-intensity chemotherapy regimens on psychological distress in early breast cancer patients. Eur. J. Cancer 38, 359–366 (2002).
Zhong, H. et al. How Does Family Function Affect the Activation Of patients With Cancer Anorexia Undergoing Chemotherapy? A Mixed Methods Study. Semin. Oncol. Nurs. 41, 151904 (2025).
Goldberg, D. & Pettke, E. Global perspectives on young-onset colorectal cancer: epidemiology, challenges, and advances. Semin. Colon Rectal Surg. 36, 101118 (2025).
Thamrin, H., Ilmiah, K. & Tirthaningsih, N. W. Profile of Colorectal Tumor in Gastroentero-Hepatology Center, Department of Internal Medicine, Dr Soetomo Hospital, Surabaya. Folia Medica Indones. 56, 15–18 (2020).
Rasjad, I. S. & Tjokroprawiro, B. A. The Role of Procalcitonin as a Prognostic Variable in Ovarian Cancer Patients at Dr. Soetomo General Hospital Surabaya. Indones. J. Cancer 15, 107–111 (2021).
Agrawal, P. & Jain, M. The Amelioration of Side Effects Associated with Chemotherapy. Curr. Cancer Ther. Rev. 21, 164–175 (2025).
Romero-Elías, M. et al. Exploring the perceived benefits of a motivational exercise program (FIT-CANCER) in colorectal cancer patients during chemotherapy treatment: A qualitative study from self-determination theory. Eur. J. Integr. Med. 65, 102328 (2024).
Mertens, B., Cuyvers, K., De Maeyer, S. & Donche, V. Unraveling low-educated adults’ motivation for second-chance education: A multidimensional perspective. Learn. Instr. 97, 102075 (2025).
Bahirwani, J. et al. Relative treatment effects of first-line chemotherapy and immunotherapy for hepatocellular carcinoma: A systematic review and meta-analysis. Cancer Pathog. Ther. (2025) doi:10.1016/J.CPT.2025.04.003.
Han, Y. et al. Effects of nurse-led interventions on enhancing patient-related outcomes in colorectal cancer management throughout the cancer care continuum: A systematic review and meta-analysis. Int. J. Nurs. Stud. 168, 105100 (2025).
Petersen, J. J., Poulsen, I., Dahn, I. & Konradsen, H. Living with late sequelae after colorectal cancer: A qualitative study on patients’ and families’ experiences. Eur. J. Oncol. Nurs. 76, 102902 (2025).
Gunnlaugsdóttir, T., Jónasdóttir, R. J., Björnsdóttir, K. & Klinke, M. E. How can family members of patients in the intensive care unit be supported? A systematic review of qualitative reviews, meta-synthesis, and novel recommendations for nursing care. Int. J. Nurs. Stud. Adv. 7, 100251 (2024).
Lei, S., Zhang, Y. & Cheah, K. S. L. Mediation of work-family support and affective commitment between family supportive supervisor Behaviour and workplace deviance. Heliyon 9, e21509 (2023).
Alhelaly, Y., Dhillon, G. & Oliveira, T. When expectation fails and motivation prevails: the mediating role of awareness in bridging the expectancy-capability gap in mobile identity protection. Comput. Secur. 134, 103470 (2023).
Wu, M. et al. Embedding relationships in hope: A qualitative study on the hope experience of patients with colorectal cancer based on Snyder’s hope theory. Eur. J. Oncol. Nurs. 77, 102916 (2025).
Arthuso, F. Z. et al. Effects of Exercise on Motivational Outcomes in Rectal Cancer Patients During and After Neoadjuvant Chemoradiation: A Phase II Randomized Controlled Trial. Semin. Oncol. Nurs. 39, 151419 (2023).
Hannah, C., Eriksson, L. E., Ramwell, A. & Llahana, S. Experiences and perspectives of patients undergoing colorectal cancer surgery: A qualitative study. Eur. J. Oncol. Nurs. 74, 102794 (2025).
Li, F. et al. Acceptance of illness and its relationship with benefit finding among patients with colorectal cancer undergoing chemotherapy: A latent profile analysis. Asia-Pacific J. Oncol. Nurs. 12, 100715 (2025).
Aprilianto, E., Lumadi, S. A. & Handian, F. I. Family Social Support and the Self-Esteem of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy. J. Public health Res. 10, (2021).
Wang, H. et al. Family participation in dignity interventions for patients with cancer receiving palliative care: A scoping review. Asia-Pacific J. Oncol. Nurs. 100796 (2025) doi:10.1016/J.APJON.2025.100796.
Mohammad-Jafari, K., Naghib, S. M. & Mozafari, M. R. Liposomal Nanoformulation-encapsulated Paclitaxel for Reducing Chemotherapy Side Effects in Lung Cancer Treatments: Recent Advances and Future Outlooks. Curr. Med. Chem. 32, 5155–5179 (2025).
El Omari, N. et al. The role of inflammation in colorectal Cancer and the preventive potential of natural compounds. J. Funct. Foods 129, 106857 (2025).
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